Supplements & Compounds
NAD+, CoQ10, creatine, mucuna, thiamine, methylene blue, cannabis and more, rated by the trials
How to use this site
Parkinson's affects movement, balance, sleep, mood and digestion, and it usually changes slowly over years. Many people want to do more than take their pills. This site starts with the things people try for themselves, then covers treatment and the research coming next.
How to read the evidence labels
Every study on this site is rated. The labels change a little by topic, but they follow the same idea:
Strongseveral good trials agreeModeratesome good evidence, or mixed resultsEarly / weaksmall, early or negative studies
A finding from comparing groups of people (an association) is weaker than one tested in a randomized trial. Words like these are explained in the glossary.
How strong is the evidence on each topic?
Number of studies rated on each page, by strength of evidence
- Strong
- Moderate
- Early, weak or no benefit
Counted from the evidence labels on each page. Most biohacks and many new treatments rest on small or early studies. Source: This site's topic pages
Show the numbers
| Strong | Moderate | Early, weak or no benefit | |
|---|---|---|---|
| Supplements & Compounds | 5 | 12 | 48 |
| Light, Heat, Cold & Devices | 0 | 18 | 35 |
| Fasting, Ketones, Sleep & Tracking | 2 | 10 | 29 |
| Exercise & Balance | 3 | 11 | 5 |
| Gut & Diet | 4 | 5 | 8 |
| Hydration & Minerals | 2 | 11 | 12 |
| Medications & Devices | 10 | 1 | 0 |
| Cell & Gene Therapy | 2 | 5 | 4 |
| Slowing Progression | 1 | 10 | 10 |
| Early Detection | 3 | 1 | 5 |
Where to start
- Want to try something yourself? Start with Biohacking, and read how to run a fair self-experiment before you buy anything.
- Newly diagnosed? Exercise & Balance has the strongest evidence of anything you can do yourself.
- Dizzy on standing, constipated or asking about minerals? See Hydration & Minerals and Gut & Diet.
- Having off periods or uneven days? See Medications & Devices.
- Wondering what's next? See Research Frontier.
This site is for general information and is not medical advice. Some supplements and devices interact with Parkinson's medicines. Talk to your neurologist or pharmacist before changing treatment, diet, supplements or exercise.